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| Vanderlinde,Frederico Argollo; Landim,Higor Frutuoso; Costa,Elson Alves; Galdino,Pablinny Moreira; Maciel,Maria Aparecida Medeiros; Anjos,Gineide Conceição dos; Malvar,David do Carmo; Côrtes,Wellington da Silva; Rocha,Fábio Fagundes da. |
| The stem bark of Anacardium occidentale L. (Anacardiaceae), commonly called cashew, is used in Brazilian traditional medicine for the treatment of gastric and inflammatory disorders. The present study was carried out to investigate the in vivo anti-inflammatory activities of the acetone extract (AE) of the stem bark of A. occidentale. We evaluated the pharmacological activities of this plant material through the analgesic, antiedematogenic and chemotaxic inhibitory effects produced by the AE. The oral administration (p.o.) of mice with the AE (0.1, 0.3 and 1.0 g/kg) or positive control indomethacin (10 mg/kg) inhibited acetic acid-induced writhing by 18.9, 35.9, 62.9 and 68.9%, respectively (ID50% = 530 mg/kg). The highest dose of the AE was able to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anacardium occidentale L./analgesic activity; Anacardium occidentale L./anti-inflammatory activity; Anacardium occidentale L./antiedematogenic activity; Anacardiaceae; Cashew. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300008 |
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